ClinicalTrials.gov + FDA Adverse Events

Every clinical trial is registered. Every adverse event report to FDA is public. Together they're the truth-tape of biotech that often diverges from press releases.

This project tracks trial result posting compliance (required within 1 year of completion — compliance is poor), detects adverse event signals using Reporting Odds Ratio analysis, and focuses on GLP-1 drugs (semaglutide, tirzepatide) for real-time safety surveillance of thyroid, pancreatitis, and suicidal ideation reports.

Data sources: ClinicalTrials.gov v2 REST API (free), openFDA drug/event API (free). No auth required for either.